5-(Benzyloxy)-1h-pyrrolo[2,3-b]pyridine
5-(Benzyloxy)-1h-pyrrolo[2,3-b]pyridine
CAS: 1036007-71-2
Molecular Formula: C14H12N2O
5-(Benzyloxy)-1h-pyrrolo[2,3-b]pyridine - Names and Identifiers
| Name | 5-(Benzyloxy)-1h-pyrrolo[2,3-b]pyridine |
| Synonyms | 5-Benzyloxy-1H-pyrrolo[2,3-b]pyridine 5-(Benzyloxy)-1h-pyrrolo[2,3-b]pyridine 1H-Pyrrolo[2,3-b]pyridine, 5-(phenylmethoxy)- |
| CAS | 1036007-71-2 |
5-(Benzyloxy)-1h-pyrrolo[2,3-b]pyridine - Physico-chemical Properties
| Molecular Formula | C14H12N2O |
| Molar Mass | 224.26 |
| Density | 1.247±0.06 g/cm3(Predicted) |
| pKa | 13.51±0.40(Predicted) |
5-(Benzyloxy)-1h-pyrrolo[2,3-b]pyridine - Introduction
5-(Benzyloxy)-1H-pyrrolo [2,3-b] pyridine, is an organic compound with the chemical formula C15H11NO. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: 5-(Benzyloxy)-1H-pyrrolo [2,3-b] pyridine as a yellow solid.
-Melting point: approximately 202-204°C.
-Solubility: Soluble in some organic solvents such as chloroform and dimethyl sulfoxide, insoluble in water.
Use:
- 5-(Benzyloxy)-1H-pyrrolo [2,3-b] pyridine is often used as an intermediate in chemical research.
-It can be used to synthesize other organic compounds, such as complexes, drugs, etc.
Preparation Method:
The preparation of 5-(benzyloxy)-1H-pyrrolo [2,3-b] pyridine generally requires a multi-step reaction:
1. First, by reacting benzyl alcohol with thionyl chloride, thionyl chloride benzyl alcohol is obtained.
2. Then, through the thermal condensation reaction with catechol, the pre-drive of 1,3-benzopyrrolyl pyridine can be obtained.
3. Finally, the predrive was reacted with sodium nitrosobromide or silver nitrite to generate the target product 5-(benzyloxy)-1H-pyrrolo [2,3-b] pyridine.
Safety Information:
The toxicity and danger of -5-(benzyloxy)-1H-pyrrolo [2,3-b] pyridine to the human body are not fully understood, so it needs to be handled with care when using it.
-During operation, good ventilation measures should be taken to avoid inhalation of dust or gas from the substance.
-Wear appropriate personal protective equipment such as protective gloves, glasses and protective clothing.
-When handling this compound, follow laboratory safety regulations and dispose of waste in accordance with regulations.
Please note that the preparation and use of chemicals should follow laboratory safety procedures and be carried out under professional guidance.
Nature:
-Appearance: 5-(Benzyloxy)-1H-pyrrolo [2,3-b] pyridine as a yellow solid.
-Melting point: approximately 202-204°C.
-Solubility: Soluble in some organic solvents such as chloroform and dimethyl sulfoxide, insoluble in water.
Use:
- 5-(Benzyloxy)-1H-pyrrolo [2,3-b] pyridine is often used as an intermediate in chemical research.
-It can be used to synthesize other organic compounds, such as complexes, drugs, etc.
Preparation Method:
The preparation of 5-(benzyloxy)-1H-pyrrolo [2,3-b] pyridine generally requires a multi-step reaction:
1. First, by reacting benzyl alcohol with thionyl chloride, thionyl chloride benzyl alcohol is obtained.
2. Then, through the thermal condensation reaction with catechol, the pre-drive of 1,3-benzopyrrolyl pyridine can be obtained.
3. Finally, the predrive was reacted with sodium nitrosobromide or silver nitrite to generate the target product 5-(benzyloxy)-1H-pyrrolo [2,3-b] pyridine.
Safety Information:
The toxicity and danger of -5-(benzyloxy)-1H-pyrrolo [2,3-b] pyridine to the human body are not fully understood, so it needs to be handled with care when using it.
-During operation, good ventilation measures should be taken to avoid inhalation of dust or gas from the substance.
-Wear appropriate personal protective equipment such as protective gloves, glasses and protective clothing.
-When handling this compound, follow laboratory safety regulations and dispose of waste in accordance with regulations.
Please note that the preparation and use of chemicals should follow laboratory safety procedures and be carried out under professional guidance.
Last Update：2024-04-09 21:01:54
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